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  <xs:element id="bntx_AssetsRecognisedAsOfAcquisitionDate" abstract="false" name="AssetsRecognisedAsOfAcquisitionDate" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="bntx_PurchaseOfCashDepositWithATermOfMoreThanThreeMonths" abstract="false" name="PurchaseOfCashDepositWithATermOfMoreThanThreeMonths" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="bntx_WeightedAverageExercisePriceOfShareOptionsExpectedToBeAllocatedInShareBasedPaymentArrangementYearThree" abstract="false" name="WeightedAverageExercisePriceOfShareOptionsExpectedToBeAllocatedInShareBasedPaymentArrangementYearThree" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="num:perShareItemType"/>
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  <xs:element id="bntx_DerivativeFinancialLiabilitiesNotDesignatedAsHedgingInstrumentsAtFairValue" abstract="false" name="DerivativeFinancialLiabilitiesNotDesignatedAsHedgingInstrumentsAtFairValue" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
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  <xs:element id="bntx_NumberOfInstrumentsOtherEquityInstrumentsAllocated" abstract="false" name="NumberOfInstrumentsOtherEquityInstrumentsAllocated" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
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  <xs:element id="bntx_AnnouncementOfResearchDevelopmentAndCommercializationCollaborationAgreementMember" abstract="true" name="AnnouncementOfResearchDevelopmentAndCommercializationCollaborationAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
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  <xs:element id="bntx_WeightedAverageExercisePriceOfShareOptionsExpectedToBeAllocatedInShareBasedPaymentArrangementYearFour" abstract="false" name="WeightedAverageExercisePriceOfShareOptionsExpectedToBeAllocatedInShareBasedPaymentArrangementYearFour" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="num:perShareItemType"/>
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  <xs:element id="bntx_OrdinarySharesNoParValueWithNationalAmountAttributableToEachOrdinaryShareMember" abstract="true" name="OrdinarySharesNoParValueWithNationalAmountAttributableToEachOrdinaryShareMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
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  <xs:element id="bntx_CurrentProvisionsForInventorRemuneration" abstract="false" name="CurrentProvisionsForInventorRemuneration" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_IdentifiableAssetsAcquiredLiabilitiesAssumedAndGoodwillNetOfBargainPurchase" abstract="false" name="IdentifiableAssetsAcquiredLiabilitiesAssumedAndGoodwillNetOfBargainPurchase" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_ProvisionsMember" abstract="true" name="ProvisionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_ThresholdAmountOfDividendByNumberOfSharesOutstandingImmediatelyFollowingInitialPublicOffering" abstract="false" name="ThresholdAmountOfDividendByNumberOfSharesOutstandingImmediatelyFollowingInitialPublicOffering" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_BIONTECHTURKEYTIBBRNLERVEKLNKARATIRMATCARETANONMRKETMember" abstract="true" name="BIONTECHTURKEYTIBBRNLERVEKLNKARATIRMATCARETANONMRKETMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_RemainingUpfrontFeesContractLiabilities" abstract="false" name="RemainingUpfrontFeesContractLiabilities" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_PurchaseOfEquityInvestmentsDesignateAtFairValueThroughOtherComprehensiveIncome" abstract="false" name="PurchaseOfEquityInvestmentsDesignateAtFairValueThroughOtherComprehensiveIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_EstimatedAllocationDateThreeMember" abstract="true" name="EstimatedAllocationDateThreeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_FederalDeferredTaxAssetsOperatingLossCarryforwards" abstract="false" name="FederalDeferredTaxAssetsOperatingLossCarryforwards" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_EstimatedAllocationDateFiveMember" abstract="true" name="EstimatedAllocationDateFiveMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_AdvancePaymentReceivedForFutureCOVID19VaccineSale" abstract="false" name="AdvancePaymentReceivedForFutureCOVID19VaccineSale" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_FinancialLiabilitiesCouponRatePerAnnum" abstract="false" name="FinancialLiabilitiesCouponRatePerAnnum" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="num:percentItemType"/>
  <xs:element id="bntx_BMBFGovernmentGrantMember" abstract="true" name="BMBFGovernmentGrantMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_BioNTechUKLimitedMember" abstract="true" name="BioNTechUKLimitedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_IntangibleAssetsNumberOfNeoantigenTargetedTherapiesUnderDevelopment" abstract="false" name="IntangibleAssetsNumberOfNeoantigenTargetedTherapiesUnderDevelopment" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="bntx_June2020PrivatePlacementMember" abstract="true" name="June2020PrivatePlacementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_NegativeFivePercentageChangeInForeignExchangeRateMember" abstract="true" name="NegativeFivePercentageChangeInForeignExchangeRateMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_UnsatisfiedOrPartiallyUnsatisfiedMember" abstract="true" name="UnsatisfiedOrPartiallyUnsatisfiedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_RevenueFromContractsWithCustomersAbstract" abstract="true" name="RevenueFromContractsWithCustomersAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="bntx_EstimatedAllocationDateFourMember" abstract="true" name="EstimatedAllocationDateFourMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_VestingDomain" abstract="true" name="VestingDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_ForeignExchangeDifferencesMember" abstract="true" name="ForeignExchangeDifferencesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_ReSanoGmbHMember" abstract="true" name="ReSanoGmbHMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_EarningsOnDerivativeInstrumentsAtFairValueThroughProfitOrLossMember" abstract="true" name="EarningsOnDerivativeInstrumentsAtFairValueThroughProfitOrLossMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_PercentageOfSharesAcquiredOfInvestmentInEquityInstrumentDesignatedAtFairValueThroughOtherComprehensiveIncome" abstract="false" name="PercentageOfSharesAcquiredOfInvestmentInEquityInstrumentDesignatedAtFairValueThroughOtherComprehensiveIncome" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="num:percentItemType"/>
  <xs:element id="bntx_JuneTwentyTwentyPrivatePlacementMember" abstract="true" name="JuneTwentyTwentyPrivatePlacementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_PurchasedServicesMember" abstract="true" name="PurchasedServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_SupervisoryBoardMember" abstract="true" name="SupervisoryBoardMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_EventsAfterReportingPeriodAbstract" abstract="true" name="EventsAfterReportingPeriodAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="bntx_KeyManagementPersonnelCompensationOtherPerformanceRelatedVariableCompensation" abstract="false" name="KeyManagementPersonnelCompensationOtherPerformanceRelatedVariableCompensation" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_OptionExercisablePeriod" abstract="false" name="OptionExercisablePeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="bntx_EffectiveInterestRateOfFinancialLiabilities" abstract="false" name="EffectiveInterestRateOfFinancialLiabilities" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="num:percentItemType"/>
  <xs:element id="bntx_WeightedAverageExercisePriceOfOtherEquityInstrumentsAllocatedInShareBasedPaymentArrangement" abstract="false" name="WeightedAverageExercisePriceOfOtherEquityInstrumentsAllocatedInShareBasedPaymentArrangement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="num:perShareItemType"/>
  <xs:element id="bntx_EstimatedAllocationDateTwoMember" abstract="true" name="EstimatedAllocationDateTwoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_BioNTechRealEstateGmbHCoKGMember" abstract="true" name="BioNTechRealEstateGmbHCoKGMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_DisclosureOfSalesAndMarketingExpensesExplanatoryTableTextBlock" abstract="false" name="DisclosureOfSalesAndMarketingExpensesExplanatoryTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="bntx_MaximumProceedsReceivableFromIssuanceOfOrdinaryShares" abstract="false" name="MaximumProceedsReceivableFromIssuanceOfOrdinaryShares" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_DisclosureOfDetailedInformationAboutEmployeeBenefitsExpenseExplanatoryTableTextBlock" abstract="false" name="DisclosureOfDetailedInformationAboutEmployeeBenefitsExpenseExplanatoryTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="bntx_OnePointNineZeroPercentageSecuredBankLoanMember" abstract="true" name="OnePointNineZeroPercentageSecuredBankLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_ForeignCurrencyChangesEffectOnLossBeforeTax" abstract="false" name="ForeignCurrencyChangesEffectOnLossBeforeTax" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_DeferredTransportationCosts" abstract="false" name="DeferredTransportationCosts" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_AmortizationOfFinancialInstruments" abstract="false" name="AmortizationOfFinancialInstruments" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_ListOfAccountingPoliciesAbstract" abstract="true" name="ListOfAccountingPoliciesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="bntx_KeyManagementPersonnelCompensationShareBasedPaymentOrdinaryShares" abstract="false" name="KeyManagementPersonnelCompensationShareBasedPaymentOrdinaryShares" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="bntx_DisclosureOfOtherOperatingExpensesExplanatoryTableTextBlock" abstract="false" name="DisclosureOfOtherOperatingExpensesExplanatoryTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="bntx_SharesIssuedPricePerShare1" abstract="false" name="SharesIssuedPricePerShare1" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="num:perShareItemType"/>
  <xs:element id="bntx_BioNTechUSIncMember" abstract="true" name="BioNTechUSIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_DisclosureOfCurrentAndDeferredTaxExpenseExplanatoryTableTextBlock" abstract="false" name="DisclosureOfCurrentAndDeferredTaxExpenseExplanatoryTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="bntx_ConvertibleNoteMember" abstract="true" name="ConvertibleNoteMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_ValuationAdjustmentMember" abstract="true" name="ValuationAdjustmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_CollaborationAgreementTerm" abstract="false" name="CollaborationAgreementTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="bntx_DisclosureOfCashAndCashEquivalentsExplanatoryTableTextBlock" abstract="false" name="DisclosureOfCashAndCashEquivalentsExplanatoryTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="bntx_TradePayablesRecognisedAsOfAcquisitionDate" abstract="false" name="TradePayablesRecognisedAsOfAcquisitionDate" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_OtherAssetsAbstract" abstract="true" name="OtherAssetsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="bntx_EmployeeStockOwnershipPlanMember" abstract="true" name="EmployeeStockOwnershipPlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_IncomeAndExpensesByNatureAxis" abstract="true" name="IncomeAndExpensesByNatureAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="bntx_FixedAssetsMember" abstract="true" name="FixedAssetsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_EquityIssuable" abstract="false" name="EquityIssuable" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_DescriptionOfAccountingPolicyForAssetsAndLiabilitiesExplanatoryPolicyTextBlock" abstract="false" name="DescriptionOfAccountingPolicyForAssetsAndLiabilitiesExplanatoryPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="bntx_PurchasesOfGoodsAndServiceRelatedPartyTransactions" abstract="false" name="PurchasesOfGoodsAndServiceRelatedPartyTransactions" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_PurchasesFromRelatedPartyTransactions" abstract="false" name="PurchasesFromRelatedPartyTransactions" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_TradePayablesMember" abstract="true" name="TradePayablesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_ShareBasedPaymentArrangementsAbstract" abstract="true" name="ShareBasedPaymentArrangementsAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="bntx_ProfessorUgurSahinMDMember" abstract="true" name="ProfessorUgurSahinMDMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_BioNTechInnovationGmbHMember" abstract="true" name="BioNTechInnovationGmbHMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_IncreaseDecreaseThroughInitialPublicOffering" abstract="false" name="IncreaseDecreaseThroughInitialPublicOffering" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_ConstructionInProgressAndAdvancePaymentsMember" abstract="true" name="ConstructionInProgressAndAdvancePaymentsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_VestingAxis" abstract="true" name="VestingAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="bntx_NumberOfEntitiesAcquired" abstract="false" name="NumberOfEntitiesAcquired" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="bntx_DisclosureOfChangesRegardingGovernmentGrantsExplanatoryTableTextBlock" abstract="false" name="DisclosureOfChangesRegardingGovernmentGrantsExplanatoryTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="bntx_IssuanceOfShareCapitalAndTreasuryShares" abstract="false" name="IssuanceOfShareCapitalAndTreasuryShares" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_AccumulatedTaxLossesInStateTaxCredits" abstract="false" name="AccumulatedTaxLossesInStateTaxCredits" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_OtherDeferredExpenses" abstract="false" name="OtherDeferredExpenses" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_NumberOfOrdinarySharesIssuable" abstract="false" name="NumberOfOrdinarySharesIssuable" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="bntx_IssuanceOfShareCapital" abstract="false" name="IssuanceOfShareCapital" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_ManagementBoardGrantMember" abstract="true" name="ManagementBoardGrantMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_ShareBasedPaymentArrangementShortTermIncentiveCompensation" abstract="false" name="ShareBasedPaymentArrangementShortTermIncentiveCompensation" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_OtherDeferredTaxesMember" abstract="true" name="OtherDeferredTaxesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_InsurancePremiumsMember" abstract="true" name="InsurancePremiumsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_RightOfUseAssetsRecognisedAsOfAcquisitionDate" abstract="false" name="RightOfUseAssetsRecognisedAsOfAcquisitionDate" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_DeferredTaxExpenseIncomeRecognisedInOtherComprehensiveIncome" abstract="false" name="DeferredTaxExpenseIncomeRecognisedInOtherComprehensiveIncome" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_DoctorOzlemTureciMDMember" abstract="true" name="DoctorOzlemTureciMDMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_NumberOfFixedInterestRateLoans" abstract="false" name="NumberOfFixedInterestRateLoans" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="bntx_DeferredExpenseCurrent" abstract="false" name="DeferredExpenseCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_CurrentObligationsUnderLeaseContractsMember" abstract="true" name="CurrentObligationsUnderLeaseContractsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_OtherLiabilitiesAbstract" abstract="true" name="OtherLiabilitiesAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="bntx_BioNTechRealEstateHoldingGmbHMember" abstract="true" name="BioNTechRealEstateHoldingGmbHMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="bntx_AuditInformationAbstract" abstract="true" name="AuditInformationAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="bntx_PurchaseOfIntangibleAssetsAndRightOfUseAssetsClassifiedAsInvestingActivities" abstract="false" name="PurchaseOfIntangibleAssetsAndRightOfUseAssetsClassifiedAsInvestingActivities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_NonRefundableUpfrontCashPayment" abstract="false" name="NonRefundableUpfrontCashPayment" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_DeferredRemunerationFromBusinessCombination" abstract="false" name="DeferredRemunerationFromBusinessCombination" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="bntx_DescriptionOfAccountingPolicyForStandardsIssuedButNotYetEffectiveExplanatoryPolicyTextBlock" abstract="false" name="DescriptionOfAccountingPolicyForStandardsIssuedButNotYetEffectiveExplanatoryPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="bntx_KeyManagementPersonnelCompensationPhantomSharesAwarded" abstract="false" name="KeyManagementPersonnelCompensationPhantomSharesAwarded" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="bntx_DisclosureOfReconciliationOfExpectedIncomeTaxBenefitToActualIncomeTaxBenefitExplanatoryTableTextBlock" abstract="false" name="DisclosureOfReconciliationOfExpectedIncomeTaxBenefitToActualIncomeTaxBenefitExplanatoryTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="bntx_CashAndCashEquivalentsTable" abstract="true" name="CashAndCashEquivalentsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="bntx_CashAndCashEquivalentsLineItems" abstract="true" name="CashAndCashEquivalentsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
</xs:schema>
